NSE
NSE Basic information
- Product Name:
- NSE
- Synonyms:
-
- 2-PHOSPHO-D-GLYCERATE HYDRO-LYASE
- NEURON SPECIFIC ENOLASE
- NEURON SPECIFIC ENOLASE, HUMAN, BRAIN
- NSE
- THERMOLABILE ANTIGEN A
- Human Neurone Specific Enolase
- 2-Phospho-D-glycerate hydro-lyase, Enolase, Neuron-specific from human brain, NSE, Thermolabile antigen A
- Neuron-specific enolase from human brain
- MW:
- 0
- Product Categories:
-
- proteins
- Mol File:
- Mol File
NSE Chemical Properties
- storage temp.
- −20°C
- form
- buffered aqueous solution
- biological source
- rabbit
- Specific Activity
- ≥10units/mg protein
Safety Information
- Hazard Codes
- B
- WGK Germany
- -
- HS Code
- 3504009000
MSDS
- Language:English Provider:SigmaAldrich
NSE Usage And Synthesis
Uses
Neuron-specific enolase from human brain has been used in a study to assess human amniotic mesenchymal stem cells in the treatment of focal cerebral ischemia. It has also been used in a study to investigate sinonasal teratocarcinosarcoma with rhabdoid features.
Biological Activity
Neuron-specific enolase (NSE) is expressed in all neuronal cell types, and its expression marks the acquisition of synaptic function. Following acute neuronal injury, NSE levels are increased in neuronal cell bodies. Increased levels of NSE in serum and cerebrospinal fluid have been used as markers for injury and neuronal cell death. Tumors derived from many cell types, including most neuronal and neuroendocrine tumors, express NSE.', 'Neuron-specific enolase promotes survival of neurons and can provide neuroprotective effects by binding to neurons in a calcium-dependent manner.
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