15(S)-HEPE
15(S)-HEPE Basic information
- Product Name:
- 15(S)-HEPE
- Synonyms:
-
- 15(S)-HEPE MaxSpec Standard
- 15(S)-HYDROXY-(5Z,8Z,11Z,13E,17Z)-EICOSAPENTAENOIC ACID
- 15(S)-HEPE
- 15(S)-HYDROXYEICOSA-5Z,8Z,11Z,13E,17Z-PENTAENOIC ACID
- 15(S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-*eicosapentaeno
- 15(S)-HYDROXY-(5Z,8Z,11Z,13E,17Z)-*EICOS APENTAENOIC
- 15(S)-Hydroxyeicosa-5Z,8Z,11Z,13E,17Z-pentaenoic acid (15(S)-HEPE)
- WLKCSMCLEKGITB-DBVSHIMFSA-N
- CAS:
- 86282-92-0
- MF:
- C20H30O3
- MW:
- 318.45
- Mol File:
- 86282-92-0.mol
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15(S)-HEPE Chemical Properties
- Boiling point:
- 488.0±45.0 °C(Predicted)
- Density
- 0.997±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
- pka
- 4.75±0.10(Predicted)
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Safety Information
- Hazard Codes
- F,Xi
- Risk Statements
- 11-36/37/38
- Safety Statements
- 16-26-36
- RIDADR
- UN 1170 3/PG 2
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
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15(S)-HEPE Usage And Synthesis
Description
15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid (Item Nos. 90110 | 90110.1 | 21908) by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma.
Definition
ChEBI: 15(S)-HEPE is a 15-HEPE that consists of (5Z,8Z,11Z,13E,17Z)-icosapentaenoic acid in which the 15-hydroxy group has S-configuration. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a 15(S)-HEPE(1-). It is an enantiomer of a 15(R)-HEPE.
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