UDP-GLUCURONOSYLTRANSFERASE 1A1 ISOZYME HUMAN Chemical Properties

storage temp. 

−70°C

form 

buffered aqueous glycerol solution

Safety Information

WGK Germany 

1

MSDS

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UDP-GLUCURONOSYLTRANSFERASE 1A1 ISOZYME HUMAN Usage And Synthesis

Description

UGT1A1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 488 amino acids (26-490 a.a) and having a molecular mass of 54.7kDa. UGT1A1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

UDP Glucuronosyltransferase 1 Family Polypeptide A1, also known as UGT1A1 has a main importance in the conjugation as well as subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT1A1 is also capable of catalyzing glucuronidation of 17beta, 17alpha, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.