ANTI-PAN NAV
ANTI-PAN NAV Basic information
- Product Name:
- ANTI-PAN NAV
- Synonyms:
-
- Anti-KAL1 / ANOSMIN antibody produced in rabbit
- Anti-Sodium Channel, Pan antibody produced in rabbit
- Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse
- ANTI-SODIUM CHANNEL, VOLTAGE GATED, PAN [SP19]
- ANTI-SP19
- ANTI-SODIUM CHANNEL (PAN)
- ANTI-PAN SODIUM CHANNEL
- ANTI-SODIUM CHANNEL (PAN) (SP19)
- MW:
- 0
- Product Categories:
-
- Alphabetical Index
- Antibodies to Ion Channels
- Antibodies to Sodium ChannelsAntibodies
- Antibodies to Voltage-Gated Ion Channels
- Clone Index
- KAntibodies
- SM-SZ
- Mol File:
- Mol File
ANTI-PAN NAV Chemical Properties
- storage temp.
- −20°C
- form
- lyophilized powder
- biological source
- rabbit
Safety Information
- Hazard Codes
- T,Xn
- Risk Statements
- 24/25-32-52/53-21/22
- Safety Statements
- 36/37-45-61
- WGK Germany
- 3
MSDS
- Language:English Provider:SigmaAldrich
ANTI-PAN NAV Usage And Synthesis
Uses
Anti-Sodium Channel, Pan antibody is suitable for use in immunohistochemistry (formalin-fixed, paraffin-embedded sections), immunoprecipitation and chemiluminescent western blot.
General Description
Voltage-gated sodium channels (VGSC) are membrane proteins that are usually present in excitable cells. These sodium channels regulate neurological functions such as the generation of action potentials in nerve cells. Alterations in neurological sodium ion channels have been associated with epilepsy, whereas mutations in cardiac sodium channels have been linked to long QT syndrome . Anti-Sodium Channel, Pan antibody is specific for the α subunit of VGSC in rats.
Biological Activity
Voltage-gated sodium channels/VGSCs (Nav) participates in nociceptive transmission. They play a key role in regulating the exchange between the extracellular and intracellular spaces. VGSCs are crucial for the initiation and firing of action potentials. They participate in neuronal excitability. Hence mutations in the VGSC genes results in several epileptic disorders.