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Methylglucamine antimonate

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Methylglucamine antimonate Basic information

Product Name:
Methylglucamine antimonate
Synonyms:
  • 1-deoxy-1-(methylamino)-,compd.withantimonicacid(1:1),d-glucito
  • 1-deoxy-1-(methylamino)-d-glucitocompd.withantimonicacid(1:1)
  • 1-deoxy-1-(methylamino)-d-glucitotrioxoantimonate(1-)
  • 2168-rp
  • glucantime
  • meglumineantimonate
  • methylglucamineantimonate
  • protostib
CAS:
133-51-7
MF:
C7H18NO8Sb
MW:
365.98
EINECS:
205-108-3
Mol File:
133-51-7.mol
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Methylglucamine antimonate Chemical Properties

storage temp. 
Refrigerator, Under inert atmosphere
solubility 
Acidic DMSO (Slightly, Sonicated), Aqueous Base (Very Slightly, Heated)
form 
Solid
color 
White to Off-White
CAS DataBase Reference
133-51-7(CAS DataBase Reference)
EPA Substance Registry System
Glucantime (133-51-7)
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Methylglucamine antimonate Usage And Synthesis

Uses

In the synthesis of surface active agents, pharmaceuticals, dyes.

Pharmaceutical Applications

N-Methylglucamine antimonate; methylaminoglucitol antimonate. The SbV content varies around 28% between batches. The major moieties are SbV–ligand complexes which are zwitterionic in solution. The activity, pharmacology and toxicology are similar to those of sodium stibogluconate, with which it is essentially interchangeable.

Clinical Use

Treatment of visceral and cutaneous leishmaniasis
Studies in Central and South America have indicated that the combination with interferon-γ is effective in the treatment of visceral and cutaneous leishmaniasis cases unresponsive to antimony alone.

Methylglucamine antimonateSupplier

J & K SCIENTIFIC LTD.
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