GALANIN (1-13)-SPANTIDE I Chemical Properties

Density 

1.22 g/mL at 25 °C(lit.)

storage temp. 

−20°C

form 

Solid

Sequence

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Arg-Pro-Lys-Pro-Gln-Gln-Trp-Phe-Trp-Leu-Leu-NH2

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

MSDS

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GALANIN (1-13)-SPANTIDE I Usage And Synthesis

Uses

Galanin (1-13)-spantide I is a chimeric peptide composed of the N-terminal fragment of galanin (amino acids 1-13) and spantide, a known substance P receptor antagonist. Galanin (1-13)-spantide I has a high affinity for spinal galanin receptor (Kd=1.16 nM). Galanin (1-13)-spantide I can be used to study the effects of galanin on feeding behavior[1][2].

References

[1] Crawley J N, et al. Galanin receptor antagonists M40 and C7 block galanin-induced feeding[J]. Brain research, 1993, 600(2): 268-272. DOI:10.1016/0006-8993(93)91382-3
[2] Xu X J, et al. New high affinity peptide antagonists to the spinal galanin receptor[J]. British journal of pharmacology, 1995, 116(3): 2076-2080. DOI:10.1111/j.1476-5381.1995.tb16414.x

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