PrDiAzK
PrDiAzK Basic information
- Product Name:
- PrDiAzK
- Synonyms:
-
- PrDiAzK
- bifunctional Cross-Linking-Amino-Acid / PrDiAzK
- L-Lysine, N6-[[[3-[(2-propyn-1-yloxy)methyl]-3H-diazirin-3-yl]methoxy]carbonyl]-
- CAS:
- 2231405-64-2
- MF:
- C13H20N4O5
- MW:
- 312.32
- Product Categories:
-
- SiChem
- Mol File:
- 2231405-64-2.mol
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PrDiAzK Chemical Properties
- Density
- 1.33±0.1 g/cm3(Predicted)
- pka
- 2.53±0.24(Predicted)
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PrDiAzK Usage And Synthesis
Uses
PrDiAzK is a bifunctional amino acid. PrDiAzK can be site-selectively incorporated into proteins in both bacterial and mammalian cell culture. PrDiAzK can be used for proteome-wide incorporation via stochastic orthogonal recoding of translation (SORT)[1]. PrDiAzK is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References
[1] Hoffmann JE, et L. A Bifunctional Noncanonical Amino Acid: Synthesis, Expression, and Residue-Specific Proteome-wide Incorporation. Biochemistry. 2018;57(31):4747-4752. DOI:10.1021/acs.biochem.8b00397
PrDiAzKSupplier
Taizhou GreenChem Pharmaceutical Co., Ltd.
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- 0514-86654616 15366892466
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Changzhou Hopschain Chemical Co.,Ltd.
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- 0519-85528066 13775048983
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Nanjing Shizhou Biology Technology Co.,Ltd
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- 13675144456
- sean.lv@synzest.com
Vicbio Biotechnology Co., Ltd.
- Tel
- 400-001-2615 13691409741
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Taizhou GreenChem Pharma-Tech Co.,Ltd
- Tel
- 15366892466
- greenchem@tzglmk.com