ABC34 Chemical Properties

Boiling point:

694.7±65.0 °C(Predicted)

Density 

1.41±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMF: 20 mg/mL; DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL; DMSO: 10 mg/mL

form 

A crystalline solid

pka

7.92±0.20(Predicted)

color 

White to off-white

ABC34 Usage And Synthesis

Description

ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). ABC34 demonstrates an IC₅₀ value greater than 25 μM for the inhibition of 9-PAHSA but is more potent in blocking the serine hydrolase ABHD6 and the palmitoyl-protein hydrolase PPT1, which are both off-targets of JJH260.