C30(-hydroxy) Ceramide (d18:1/30:0) Chemical Properties

Boiling point:

828.2±65.0 °C(Predicted)

Density 

0.922±0.06 g/cm3(Predicted)

solubility 

Chloroform:Methanol (5:1): Soluble; DMF: Soluble; Ethanol: Heated

form 

A solid

pka

13.54±0.20(Predicted)

C30(-hydroxy) Ceramide (d18:1/30:0) Usage And Synthesis

Description

C30(ω-hydroxy) Ceramide is a bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis. C30(ω-hydroxy) Ceramide is vital to skin barrier functions and has a role in maturation of epidermis cells of the spermatozoa/testes. C30(ω-hydroxy) Ceramide deficiency causes defective skin-water permeability barrier function and neonatal lethality in elongation of very long chain fatty acids-4 (ELOVL4) deficient mice. [Matreya, LLC. Catalog No. 2080]

Definition

ChEBI: N-(omega-hydroxytriacontanoyl)sphingosine is an N-acylsphingosine that has omega-hydroxytriacontanoyl as the acyl group. A bioactive sphingolipid found in the stratum corneum layer of mammalian epidermis. It is a N-acylsphingosine, an omega-hydroxy-ultra-long chain fatty acylceramide and a N-(omega-hydroxy-ultra-long chain fatty acyl)sphingosine. It is functionally related to an omega-hydroxytriacontanoic acid.