Basic information Safety Supplier Related

1,4-DITHIOTHREITOL-D10

Basic information Safety Supplier Related

1,4-DITHIOTHREITOL-D10 Basic information

Product Name:
1,4-DITHIOTHREITOL-D10
Synonyms:
  • 1,1,2,3,4,4-hexadeuterio-2,3-dideuteriooxy-1,4-bis(deuteriosulfanyl)butane
  • DL-1,4-DITHIOTHREITOL (D10)
  • 1,4-DITHIOTHREITOL-D10, 98 ATOM % D
  • cleland's reagent-d10
  • dl-dithiothreitol-d10
  • 1,4-DITHIOTHREITOL-D10
  • DL-Dithiothreitol-d10 98 atom % D, 98% (CP)
  • DL-Dithiothreitol-d??
CAS:
302912-05-6
MF:
C4D10O2S2
MW:
164.31
Mol File:
302912-05-6.mol
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1,4-DITHIOTHREITOL-D10 Chemical Properties

Melting point:
42-44 °C(lit.)
storage temp. 
2-8°C
form 
solid
CAS Number Unlabeled
27565-41-9
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
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1,4-DITHIOTHREITOL-D10 Usage And Synthesis

Uses

DL-dithiothreitol-d10 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24(1): 183. DOI:10.1186/s12935-024-03374-6

1,4-DITHIOTHREITOL-D10Supplier

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