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3'-O-MOE-G(iBu)-2'-phosphoramidite

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3'-O-MOE-G(iBu)-2'-phosphoramidite Basic information

Product Name:
3'-O-MOE-G(iBu)-2'-phosphoramidite
Synonyms:
  • 3'-O-MOE-G(iBu)-2'-phosphoramidite
  • 5’-O-DMTr-N2-iso-butyroyl-3’-O-(2-methoxy ethyl)guanosine-2’-CED-phosphoramidite
  • 3’-O-MOE-G(iBu)-2’-phosphor
  • Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
  • 3’-O-MOE-G(iBu)-2’-phos phoramidite
CAS:
256224-06-3
MF:
C47H60N7O10P
MW:
914.01
Mol File:
256224-06-3.mol
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3'-O-MOE-G(iBu)-2'-phosphoramidite Chemical Properties

pka
9.16±0.20(Predicted)
InChIKey
BWLKVJLYUDLOLH-KEFUZROQNA-N
SMILES
C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=NC3C(NC(NC(=O)C(C)C)=NC2=3)=O)[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]1OCCOC |&1:25,27,44,59,r|
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3'-O-MOE-G(iBu)-2'-phosphoramidite Usage And Synthesis

Description

3’-O-MOE-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)

Chemical Properties

White to off-white powder

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