dinutuximab Chemical Properties

form 

Liquid

color 

Colorless to light yellow

Safety Information

Hazardous Substances Data

1363687-32-4(Hazardous Substances Data)

dinutuximab Usage And Synthesis

Uses

Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab potently enlongs event-free survival and overall survival, in high-risk neuroblastoma treatment, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (interleukin-2 [IL-2]), and isotretinoin (13-cis-retinoic acid [RA])[1].

References

[1] Ploessl C, et al. Dinutuximab: An Anti-GD2 Monoclonal Antibody for High-Risk Neuroblastoma. Ann Pharmacother. 2016 May;50(5):416-22. DOI:10.1177/1060028016632013

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