Basic information Safety Supplier Related

N,N-Dimethyltryptamine

Basic information Safety Supplier Related

N,N-Dimethyltryptamine Basic information

Product Name:
N,N-Dimethyltryptamine
Synonyms:
  • N,N-Dimethyltryptamine (DMT) solution
  • N,N-DIMETHYLTRYPTAMINE METHANOL*SOLUTION
  • 1H-Indole-3-ethanamine, N,N-dimethyl-
  • 2-(1H-Indol-3-yl)-N,N-dimethylethanamine
  • 2-(3-Indolyl)ethyldimethylamine
  • 2-(indol-3-yl)ethyldimethylamine
  • 3-(2-(dimethylamino)ethyl)-indol
  • 3-(2-Dimethylaminoethyl)indole
CAS:
61-50-7
MF:
C12H16N2
MW:
188.27
EINECS:
200-508-4
Product Categories:
  • Amines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Neurochemicals
  • Pharmaceuticals
  • Isotope Labelled Compounds
  • Pharmaceutical Intermediates
Mol File:
61-50-7.mol
More
Less

N,N-Dimethyltryptamine Chemical Properties

Melting point:
42-44°C
Boiling point:
bp 60-80°
Density 
1.0580 (rough estimate)
refractive index 
1.5430 (estimate)
Flash point:
9℃
storage temp. 
Store at -20°C
solubility 
DMSO: soluble15mg/mL, clear
form 
powder
pka
8.68 (ethanol-water)
color 
white to beige
NIST Chemistry Reference
N,N-Dimethyltryptamine(61-50-7)
More
Less

Safety Information

RIDADR 
1544
WGK Germany 
3
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
61-50-7(Hazardous Substances Data)
DEA Controlled Substances
CSCN: 7435
CAS SCH: I
NARC: N
More
Less

N,N-Dimethyltryptamine Usage And Synthesis

Chemical Properties

Tan Solid

Uses

It is an endogenous Sigma-1 receptor regulator.

Uses

A labelled endogenous Sigma-1 receptor regulator.

Definition

ChEBI: A tryptamine derivative having two N-methyl substituents on the side-chain.

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 3738, 1994 DOI: 10.1021/jo00092a046

General Description

Dimethyltryptamine is a very weak hallucinogen, activeonly by inhalation or injection, with a short duration of action.It possesses pronounced sympathomimetic (NE) sideeffects.

Biological Activity

Endogenous σ 1 receptor ligand and psychoactive plant compound (K i = 14.8 μ M). Binding to σ 1 inhibits voltage-gated Na + channels and is responsible for the behavioral effects of DMT. Also a 5-HT 2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (K i = 4.0 μ M).

N,N-DimethyltryptamineSupplier