N,N-Dimethyltryptamine
N,N-Dimethyltryptamine Basic information
- Product Name:
- N,N-Dimethyltryptamine
- Synonyms:
-
- N,N-Dimethyltryptamine (DMT) solution
- N,N-DIMETHYLTRYPTAMINE METHANOL*SOLUTION
- 1H-Indole-3-ethanamine, N,N-dimethyl-
- 2-(1H-Indol-3-yl)-N,N-dimethylethanamine
- 2-(3-Indolyl)ethyldimethylamine
- 2-(indol-3-yl)ethyldimethylamine
- 3-(2-(dimethylamino)ethyl)-indol
- 3-(2-Dimethylaminoethyl)indole
- CAS:
- 61-50-7
- MF:
- C12H16N2
- MW:
- 188.27
- EINECS:
- 200-508-4
- Product Categories:
-
- Amines
- Heterocycles
- Intermediates & Fine Chemicals
- Neurochemicals
- Pharmaceuticals
- Isotope Labelled Compounds
- Pharmaceutical Intermediates
- Mol File:
- 61-50-7.mol
N,N-Dimethyltryptamine Chemical Properties
- Melting point:
- 42-44°C
- Boiling point:
- bp 60-80°
- Density
- 1.0580 (rough estimate)
- refractive index
- 1.5430 (estimate)
- Flash point:
- 9℃
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble15mg/mL, clear
- form
- powder
- pka
- 8.68 (ethanol-water)
- color
- white to beige
- NIST Chemistry Reference
- N,N-Dimethyltryptamine(61-50-7)
Safety Information
- RIDADR
- 1544
- WGK Germany
- 3
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Hazardous Substances Data
- 61-50-7(Hazardous Substances Data)
- DEA Controlled Substances
- CSCN: 7435
CAS SCH: I
NARC: N
N,N-Dimethyltryptamine Usage And Synthesis
Chemical Properties
Tan Solid
Uses
It is an endogenous Sigma-1 receptor regulator.
Uses
A labelled endogenous Sigma-1 receptor regulator.
Definition
ChEBI: A tryptamine derivative having two N-methyl substituents on the side-chain.
Synthesis Reference(s)
The Journal of Organic Chemistry, 59, p. 3738, 1994 DOI: 10.1021/jo00092a046
General Description
Dimethyltryptamine is a very weak hallucinogen, activeonly by inhalation or injection, with a short duration of action.It possesses pronounced sympathomimetic (NE) sideeffects.
Biological Activity
Endogenous σ 1 receptor ligand and psychoactive plant compound (K i = 14.8 μ M). Binding to σ 1 inhibits voltage-gated Na + channels and is responsible for the behavioral effects of DMT. Also a 5-HT 2A receptor agonist and inhibitor of 5-HT uptake at plasma membrane serotonin transporters (SERT) (K i = 4.0 μ M).
N,N-Dimethyltryptamine(61-50-7)Related Product Information
- Indometacin
- 1-METHYL-DL-TRYPTOPHAN
- 5-Methoxytryptamine
- 3-(2-Aminoethyl)-6-methoxyindole
- Dimethyl sulfate
- Dimethyl ether
- Dimethyl carbonate
- Dimethyl sulfoxide
- ETHANE
- Indole
- Indole-3-acetic acid
- Dimethyl sulfide
- Dimethyl fumarate
- N,N-Dimethylcyclohexylamine
- N,N-Dimethylformamide
- N,N-Dimethyldodecylamine
- N,N-Dimethylallylamine
- Tryptamine
- Dimethyltryptamine