METHYL CIS CIS-11 14-EICOSADIENOATE Chemical Properties

Boiling point:

396.6±11.0 °C(Predicted)

Density 

0.881±0.06 g/cm3(Predicted)

storage temp. 

−20°C

solubility 

DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 0.5 mg/ml

BRN 

2506058

Safety Information

WGK Germany 

3

F 

8-10-23

METHYL CIS CIS-11 14-EICOSADIENOATE Usage And Synthesis

Description

11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid , a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (K_i = 3.1 μM) and inhibits the binding of LTB₄ to its receptor on neutrophils (K_i = 3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance. Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.

Definition

ChEBI: Cis-11,14-eicosadienoic acid methyl ester is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of (11Z,14Z)-icosadienoic acid with methanol. It has a role as an animal metabolite. It is a fatty acid methyl ester and a polyunsaturated fatty ester. It is functionally related to an (11Z,14Z)-icosadienoic acid.

METHYL CIS CIS-11 14-EICOSADIENOATE(61012-46-2)Related Product Information

• Carbon dioxide
• Eicosapentaenoic acid ethyl ester
• cis-11-Eicosenoic acid