1H-Imidazole-1-carboxylic acid, (1R)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-[[[(2R)-3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-[(1H-imidazol-1-ylcarbonyl)oxy]propyl][4-(3-oxo-4-morpholinyl)phenyl]amino]methyl]ethyl ester Chemical Properties

Melting point:

216-217°C

Boiling point:

1028.5±75.0 °C(Predicted)

Density 

1.51±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Acetontrile (Slightly), DMSO (Slightly), Methanol (Slightly)

pka

3.49±0.10(Predicted)

form 

Solid

color 

Off-White to Light Yellow

Stability:

Not stable in Solution

1H-Imidazole-1-carboxylic acid, (1R)-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-1-[[[(2R)-3-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2-[(1H-imidazol-1-ylcarbonyl)oxy]propyl][4-(3-oxo-4-morpholinyl)phenyl]amino]methyl]ethyl ester Usage And Synthesis

Uses

(1R)?-?2-?(1,?3-?Dihydro-?1,?3-?dioxo-?2H-?isoindol-?2-?yl)?-?1-?[[[(2R)?-?3-?(1,?3-?dihydro-?1,?3-?dioxo-?2H-?isoindol-?2-?yl)?-?2-?[(1H-?imidazol-?1-?ylcarbonyl)?oxy]?propyl]?[4-?(3-?oxo-?4-?morpholinyl)?phenyl]?amino]?methyl]?ethyl ester 1H-?Imidazole-?1-?carboxylic Acid is an impurity of Rivaroxaban (R538000), a novel antithrombotic agent that is highly potent and selective.