(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE Chemical Properties

Boiling point:

65-67 °C

Density 

0.938 g/mL at 25 °C

Flash point:

−4 °F

form 

Powder

color 

White to off-white to pale brown

Safety Information

Hazard Codes 

F,C,Xn

Risk Statements 

11-14-19-22-34-40-37-36/37/38

Safety Statements 

16-26-33-36-36/37/39-45-36/37

RIDADR 

UN 2924 3/PG 2

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE Usage And Synthesis

Uses

(1,3-Dioxolan-2-ylmethyl)magnesium bromide is a Grignard reagent that can be used to prepare:

• 3-[¹¹C]-Propionaldehyde, a key intermediate for the synthesis of radiolabeled compound [¹¹C]SN-38, wherein SN-38 is 7-ethyl-10-hydroxy camptothecin.
• 1-[(S)-2,2-Dimethyl-(1,3)-dioxolan-4-yl]-4-(1,3-dioxolan2-yl)-2-ol by reacting with D-glyceraldehyde, which is further used to synthesize unsaturated nucleosides.
• A bicyclo carboxylate intermediate, which is employed in the total synthesis of spirovibsanin A.

(1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE(180675-22-3)Related Product Information

• 2-(1,3-Dioxolan-2-yl)ethylmagnesium bromide
• (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide
• Magnesium bromide
• (1,3-DIOXOLAN-2-YLMETHYL)MAGNESIUM BROMIDE
• Ethylmagnesium bromide