CONCANAMYCIN B
CONCANAMYCIN B Basic information
- Product Name:
- CONCANAMYCIN B
- Synonyms:
-
- CONCANAMYCIN B
- 8-Deethyl-8-methylconcanamycin A
- ConcanaMycin B (high purity)
- MCH 210
- S 45B
- Oxacyclooctadeca-3,5,13,15-tetraen-2-one, 18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8,10-dihydroxy-3,17-dimethoxy-5,7,9,11,13-pentamethyl-, (3Z,5E,7R,8R,9S,...
- CAS:
- 81552-33-2
- MF:
- C45H73NO14
- MW:
- 852.06
- Product Categories:
-
- Antibiotic
- Mol File:
- 81552-33-2.mol
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CONCANAMYCIN B Chemical Properties
- Boiling point:
- 960.2±65.0 °C(Predicted)
- Density
- 1.20±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- White to off-white solid.
- pka
- 12.46±0.70(Predicted)
- color
- White to off-white
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CONCANAMYCIN B Usage And Synthesis
Uses
Concanamycin B is a macrocyclic lactone originally isolated from Streptomyces diastatochromogenes in 1982 as a potent inhibitor of the proliferation of mouse splenic lymphocytes stimulated by concanavalin A. Like other concanamycins and bafilomycins, concanamycin B inhibits vacuolar H(+)-ATPase. Concanamycin B inhibits the expression of newly-synthesized MHC class II molecules and suppresses bone resorption in vitro.
Uses
Concanamycin B is an antibiotic and inhibitor of vacuolar-type H+-ATPase.
storage
+4°C
CONCANAMYCIN BSupplier
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Lynnchem
- Tel
- 86-(0)29-85992781 17792393971
- info@lynnchem.com
Novachemistry
- Tel
- 44-20819178-90 02081917890
- info@novachemistry.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel
- +86-400-002-6226 13028896684
- sales@rrkchem.com