Sodium glycocholate hydrate Chemical Properties

Melting point:

210-215 °C (subl.)(lit.)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

Ethanol (Slightly, Sonicated), DMSO (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

BRN 

3854517

Safety Information

Safety Statements 

24/25

WGK Germany 

3

RTECS 

MB9265100

F 

3-9

HS Code 

29242990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

Sodium glycocholate hydrate Usage And Synthesis

Uses

Sodium glycocholate hydrate has been used in a study to assess serum total bile acids via a fluorimetric and enzymatic method. It has also been used in a study to investigate its effect on micelle formation and solubilization of testosterone.

Application

Sodium glycocholate hydrate is used to determine serum total bile acids by fluorimetric and enzymatic methods.
It has also been used in in vitro studies to investigate its effect on micelle formation and solubilization of testosterone.
This compound is considered a detergent used to solubilize fats for absorption.
This chemical product is synthetically derived from a natural compound, cholic acid.
Sodium glycocholate hydrate has been tested in the laboratory for its ability to form a liposomal delivery system to enhance oral insulin delivery. The in vitro results demonstrated that sodium glycocholate liposomes showed promising activity and can be useful to create a new approach to orally deliver insulin more efficiently.

Definition

ChEBI: Glycocholic acid sodium salt hydrate is a bile acid glycine conjugate.

General Description

Sodium glycocholate hydrate is a conjugated bile salt and an ionic biologic detergent.

Sodium glycocholate hydrate(338950-81-5)Related Product Information

• Glycochenodeoxycholic acid sodium salt
• Sodium taurodeoxycholate hydrate
• Glycocholic acid