4'-Aminoacetanilide Chemical Properties

Melting point:

164-167 °C(lit.)

Boiling point:

267 °C

Density 

1.1392 (rough estimate)

refractive index 

1.6180 (estimate)

Flash point:

195°C

storage temp. 

Store below +30°C.

solubility 

65g/l slightly soluble

pka

14.75±0.70(Predicted)

form 

Fine Crystalline Powder

Colour Index 

76005

color 

Pink to brown

PH

7.2 (1g/l, H2O, 20℃)

Water Solubility 

0.1-1 g/100 mL at 25 ºC

Sensitive 

Air Sensitive

Merck 

14,411

BRN 

742888

CAS DataBase Reference

122-80-5(CAS DataBase Reference)

NIST Chemistry Reference

Acetamide, N-(4-aminophenyl)-(122-80-5)

EPA Substance Registry System

4'-Aminoacetanilide (122-80-5)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36-42/43-20/21/22-R36

Safety Statements 

22-26-36/37-39-36-S39-S26

WGK Germany 

1

RTECS 

AD8225000

F 

8-9-23

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29242995

MSDS

• Language:English Provider:N-Acetyl-p-phenylenediamine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4'-Aminoacetanilide Usage And Synthesis

Chemical Properties

PINK TO BROWN FINE CRYSTALLINE POWDER

Uses

Intermediate in the manufacture of azo dyes, pharmaceuticals.

General Description

White or slightly reddish solid.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Hazard

Moderate toxicity by ingestion.

Fire Hazard

Flash point data are not available for 4'-Aminoacetanilide, but 4'-Aminoacetanilide is probably combustible.

Purification Methods

Crystallise the anilide from water. It has an unstable crystalline form with m 141o. It has IR: max (CCl4) 1681cm-1. [Beilstein 13 H 94, 13 I 28, 13 II 50, 13 III 166, 13 IV 137.]

4'-Aminoacetanilide(122-80-5)Related Product Information

• N,N-Diethyl-1,4-phenylenediamine
• p-Phenylenediamine dihydrochloride
• 2-BENZOYLACETANILIDE
• 4-Aminodiphenylamine
• 4'-Nitroacetanilide
• p-Acetotoluidide
• N,N'-(1,4-Phenylene)bis(acetoacetamide)
• Acetamide
• Acetyl coenzyme A sodium salt
• Acetyl chloride
• N,N,N',N'-Tetramethyl-1,4-phenylenediamine
• 1,4-Diamino-2-nitrobenzene
• N-Acetyl-L-cysteine
• o-Phenylenediamine
• N-Acetylsulfanilyl chloride
• N,N-Dimethyl-1,4-phenylenediamine
• Acetaminophen
• Acetylacetone