(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Basic information
- Product Name:
- (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- Synonyms:
-
- sk&f77434
- (+/-)-SKF-38393, N-ALLYL-, HYDROBROMIDE
- (+/-)-SKF-77434 HYDROBROMIDE
- SKF 77434 HYDROBROMIDE
- (+/-)-N-ALLYL-SKF-38393 HYDROBROMIDE
- 2,3,4,5-TETRAHYDRO-1-PHENYL-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
- (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- (+)-SKF-38393, N-ALLYL-, HYDROBROMIDE D1 DOPAMINE AGONIST
- CAS:
- 104422-04-0
- MF:
- C19H21NO2
- MW:
- 295.38
- Mol File:
- 104422-04-0.mol
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(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties
- storage temp.
- 2-8°C
- solubility
- ethanol: 3.2 mg/mL
- form
- solid
- color
- white or off-white
MSDS
- Language:English Provider:SigmaAldrich
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(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Usage And Synthesis
Uses
N-Allyl-(+/-)-SKF-38393 hydrobromide is a selective dopamine D1-like receptor partial agonist.
Definition
ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, an allyl substituent at position 3 and two hydroxy substituents at positions 7 and 8. Selective dopamine D1-like receptor partial agonist (IC50 values are 19 7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
Biological Activity
Selective dopamine D 1 -like receptor partial agonist (IC 50 values are 19.7 and 2425 nM for binding to D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo .
(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDESupplier
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(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE(104422-04-0)Related Product Information
- (±)-SKF-77434 hydrobromide, (±)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
- 1-PHENYL-2,3,4,5-TETRAHYDRO-1H-BENZAZEPINE
- R(+)-6-BROMO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- 6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
- (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- 1-N-ALLYL-3-PHENYL-2,3,4,5-TERAHYDRO-BENZO(D)AZEPINE
- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL
- (+/-)-SKF-38393 HYDROCHLORIDE