(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Basic information
- Product Name:
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- Synonyms:
-
- (±)-SKF 82958;CHLORO-APB
- (+/-)-SKF-82958 HYDROBROMIDE
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- 6-CHLORO-N-ALLYL-SKF-38393 HYDROBROMIDE
- SK&F 82958
- (±)-SKF-82958 hydrobromide, 6-Chloro-N-allyl-SKF-38393 hydrobromide, (±)-6-Chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
- 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-1H-3-benzazepine-7,8-diol
- 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-3-(2-propenyl)-
- CAS:
- 80751-65-1
- MF:
- C19H20ClNO2
- MW:
- 329.82
- Mol File:
- 80751-65-1.mol
More
Less
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties
- Boiling point:
- 473.7±45.0 °C(Predicted)
- Density
- 1.234±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: 3.7 mg/mL
- form
- solid
- pka
- 8.73±0.40(Predicted)
- color
- tan
MSDS
- Language:English Provider:SigmaAldrich
More
Less
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Usage And Synthesis
Uses
Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.
Definition
ChEBI: 9-chloro-5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is a benzazepine.
Biochem/physiol Actions
Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDESupplier
T&W GROUP
- Tel
- 021-61551611 13296011611
- contact@trustwe.com
Shanghai T&W Pharmaceutical Co., Ltd.
- Tel
- +86 21 61551611
SynAsst Chemical.
- Tel
- 021-60343070
Finetech Industry Limited
- Tel
- 027-87465837 19945049750
- sales@finetechnology-ind.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
More
Less
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE(80751-65-1)Related Product Information
- 2-(3-Chlorophenyl)ethylamine
- 3-CHLOROCATECHOL
- Dopamine
- 3-CHLORO-5-METHYLPHENOL
- 3-CHLORO-4-METHYLPHENOL
- Hordenine hydrochloride
- N,N-BIS(2-PHENYL-ETHYL)-N-METHYL-AMINE
- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL
- N,beta-Dimethylphenethylamine hydrochloride
- [2-(3-CHLORO-PHENYL)-ETHYL]-ETHYL-AMINE
- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
- N-ISOBUTYL-2-PROPEN-1-AMINE
- 6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
- (+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- [2-(3-CHLORO-PHENYL)-ETHYL]-METHYL-AMINE
- ethyl(1-phenylethyl)benzene