Encelimab Chemical Properties

form 

Liquid

color 

Colorless to light yellow

Encelimab Usage And Synthesis

Uses

Encelimab is an anti-LAG3 antibody. Encelimab blocks the interaction between LAG-3 and MHC II, and enhances T-cell activation. Encelimab alone or in combination with an anti-PD-1 antibody reduces tumor size in a lymphoma mice model (A20 cell xenograft)[1].

References

[1] Perez-Santos M, et al. Approaches for development of LAG-3 inhibitors and the promise they hold as anticancer agents. Expert Opin Drug Discov. 2022 Dec;17(12):1341-1355. DOI:10.1080/17460441.2022.2148652

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