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pyridoxamine

Basic information Safety Supplier Related

pyridoxamine Basic information

Product Name:
pyridoxamine
Synonyms:
  • 4-(azaniumylmethyl)-5-(hydroxymethyl)-2-methylpyridin-3-olate
  • 4-(aminomethyl)-5-(hydroxymethyl)-2-methyl-pyridin-3-ol
  • 3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinemethanamine
  • 4-Aminomethyl-5-hydroxy-6-methyl-3-pyridinemethanol
  • Pyridorin
  • 4-(aminomethyl)-2-methyl-5-methylol-pyridin-3-ol
  • PyridoxaMine-d4
  • Pyridoxylamine
CAS:
85-87-0
MF:
C8H12N2O2
MW:
168.19
EINECS:
201-640-5
Mol File:
85-87-0.mol
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pyridoxamine Chemical Properties

Melting point:
193-193.5 °C
Boiling point:
460.1±40.0 °C(Predicted)
Density 
1.282±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.98±0.10(Predicted)
color 
Pale Yellow
Stability:
Hygroscopic
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pyridoxamine Usage And Synthesis

Definition

ChEBI: Pyridoxamine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a mouse metabolite, an iron chelator and a nephroprotective agent. It is a hydroxymethylpyridine, a monohydroxypyridine, an aminoalkylpyridine and a vitamin B6. It is a conjugate base of a pyridoxaminium(1+).

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