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ethylbis(3-phenylpropyl)ammonium chloride

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ethylbis(3-phenylpropyl)ammonium chloride Basic information

Product Name:
ethylbis(3-phenylpropyl)ammonium chloride
Synonyms:
  • ethylbis(3-phenylpropyl)ammonium chloride
  • Einecs 227-793-8
  • alverine hydrochloride
CAS:
5982-87-6
MF:
C20H28ClN
MW:
317.89602
EINECS:
227-793-8
Mol File:
5982-87-6.mol
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ethylbis(3-phenylpropyl)ammonium chloride Usage And Synthesis

Uses

Alverine hydrochloride citrate is a 5-HT1A receptor antagonist, with an IC50 of 101 nM.

Definition

ChEBI: The hydrochloride salt of alverine.

References

[1] Coelho, A.M., et al., Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype. J Pharm Pharmacol, 2001. 53(10): p. 1419-26. DOI:10.1211/0022357011777783
[2] Hayase, M., et al., Evolving mechanisms of action of alverine citrate on phasic smooth muscles. Br J Pharmacol, 2007. 152(8): p. 1228-38. DOI:10.1038/sj.bjp.0707496

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