Basic information Safety Supplier Related

guluronic acid

Basic information Safety Supplier Related

guluronic acid Basic information

Product Name:
guluronic acid
Synonyms:
  • guluronic acid
  • Einecs 239-860-9
  • Guluronic acid sodium salt
  • G2013
  • L-Guluronic Acid Sodium Salt/Guluronic acid
CAS:
15769-56-9
MF:
C6H10O7
MW:
194.14
EINECS:
239-860-9
Product Categories:
  • Biochemical reagents, oligosaccharide
Mol File:
15769-56-9.mol
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guluronic acid Chemical Properties

form 
Solid
color 
White to off-white
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guluronic acid Usage And Synthesis

Description

Glucuronic acid is a sugar acid derived from glucose, with its sixth carbon atom oxidized to a carboxylic acid. In living beings, this primary oxidation occurs with UDP-α-D-glucose (UDPG), not with the free sugar.
Glucuronic acid, like its precursor glucose, can exist as a linear (carboxo-)aldohexose (<1%), or as a cyclic hemiacetal (furanose or pyranose). Aldohexoses such as D-glucose are capable of forming two furanose forms (α and β) and two pyranose forms (α and β). By the Fischer convention, glucuronic acid has two stereoisomers (enantiomers), D- and L-glucuronic acid, depending on its configuration at C-5. Most physiological sugars are of the D-configuration. Due to ring closure, cyclic sugars have another asymmetric carbon atom (C-1), resulting in two more stereoisomers, named anomers. Depending on the configuration at C-1, there are two anomers of glucuronic acid, α- and β-form. In β-D-glucuronic acid the C-1 hydroxy group is on the same side of the pyranose ring as the carboxyl group. In the free sugar acid, the β-form is prevalent (~64%), whereas in the organism, the α-form UDP-α-D-glucuronic acid (UDPGA) predominates.

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