DIACETYL BENZOYL LATHYROL
DIACETYL BENZOYL LATHYROL Basic information
- Product Name:
- DIACETYL BENZOYL LATHYROL
- Synonyms:
-
- DIACETYL BENZOYL LATHYROL
- (1aR,2E,4aR,6S,7S,7aR,8R,11aS)-4a,8-Bis(acetyloxy)-7-(benzoyloxy)-1,1a,4a,5,6,7,7a,8,9,10,11,11a-dodecahydro-1,1,3,6-tetramethyl-9-methylene-4H-cyclopenta[a]cyclopropa[f]cycloundecen-4-one
- 5,15-Diacetyl-3-benzoyllathyrol
- Euphorbia factor L3
- Phytoclear EL-1
- Lathyrol-3,15-diacetate-5-benzoate
- Eupho
- Euphporbia factor L3
- CAS:
- 218916-52-0
- MF:
- C31H38O7
- MW:
- 522.63
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 218916-52-0.mol
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DIACETYL BENZOYL LATHYROL Chemical Properties
- Boiling point:
- 595.5±50.0 °C(Predicted)
- Density
- 1.19
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- color
- White to off-white
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DIACETYL BENZOYL LATHYROL Usage And Synthesis
Cytotoxicity
EFL3 of lathyrane diterpenoids showed potent cytotoxicity to A549 cells. Furthermore, EFL3 induced apoptosis of A549 cells through mitochondrial pathway with involvement of loss of ΔΨm, release of cytochrome c.
The cytotoxicity of EFL3 was determined by an MTT assay to evaluate its antitumor activity. The results showed that EFL3 inhibited cell proliferation in a concentration-dependent manner in A549 cells after 72 h treatment. The IC50 of EFL3 for A549 cells was 34.04 ± 3.99 μM. The data suggested that EFL3 exhibited potent cytotoxicity towards these cells.
The results showed that EFL3 showed more potent cytotoxicity to A549 cellsMolecules 2011, 16 3225 than EFL1 (P < 0.01).
Uses
Lathyrol-3,15-diacetate-5-benzoate could induce apoptosis in lung cancer A549 cells through the mitochondrial pathway including the loss of mitochondrial potential and release of cytochrome c.
Definition
ChEBI: Diacetyl benzoyl lathyrol is a diterpenoid.
DIACETYL BENZOYL LATHYROLSupplier
Huzhou ZhanShu Biotechnology Co.,Ltd Gold
- Tel
- 0572-8889530 18167260939
- zsubio@163.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
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Shandong Xiya Chemical Co., Ltd
- Tel
- 4009903999 13355009207
- 3007715519@qq.com
Sichuan Kulinan Technology Co., Ltd
- Tel
- 400-1166-196 18981987031
- cdhxsj@163.com
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DIACETYL BENZOYL LATHYROL(218916-52-0)Related Product Information
- 17-Hydroxyisolathyrol
- Ingenol mebutate
- 20-DEOXYINGENOL
- Dodecanoic acid ingenol ester
- (1aR,7bR)-1aα,2,7aα,13,14,14aα-Hexahydro-1,1,6,6,9,9,11,13α-octamethyl-10aαH-2α,12aα-methano-1H,4H-cyclopropa[5,6][1,3]dioxolo[2',3']cyclopenta[1',2':9,10]cyclodeca[1,2-d][1,3]dioxin-15-one
- Ingenol
- Euphorbia factor L1
- (6R)-6,6aβ,7aβ,8,9,12,12a,12bβ-Octahydro-12α,12aα-dihydroxy-2,2,7,7,9β,11-hexamethyl-7H-6β,9aβ-methano-4H-cyclopenta[9,10]cyclopropa[5,6]cyclodeca[1,2-d]-1,3-dioxin-13-one
- Lathyrol
- Euphorbia factor L7b
- Euphorbia factor L8
- euphorbiafactor L2
- Euphorbia factor L7a
- DIACETYL BENZOYL LATHYROL
- TRANS-CYCLODODECENE