DAPHNIN Chemical Properties

Melting point:

216-217 °C

alpha 

D22 -124° (15 mg in 4 ml MeOH); D22 -115° (abs MeOH) (Wessely, Sturm); D15 -84.2° (MeOH) (Hattori)

Boiling point:

670.0±55.0 °C(Predicted)

Density 

1.679±0.06 g/cm3(Predicted)

storage temp. 

-20°C, protect from light

pka

6.87±0.20(Predicted)

form 

Solid

color 

Light brown to khaki

DAPHNIN Usage And Synthesis

Uses

Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever[1][2].

Definition

ChEBI: Daphnin is a beta-D-glucoside. It is functionally related to a 7,8-dihydroxycoumarin.

References

[1] Zhu J, et al. Investigation the interaction of Daphnin with human serum albumin using optical spectroscopy and molecular modeling methods. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Sep;95:252-7. DOI:10.1016/j.saa.2012.04.099
[2] Shakeel-U-Rehman, et al. Isolation, characterisation and antibacterial activity studies of coumarins from Rhododendron lepidotum Wall. ex G. Don, Ericaceae. Rev. bras. farmacogn. vol.20 no.6 Curitiba Dec. 2010 Epub Nov 12, 2010.

DAPHNIN(486-55-5)Related Product Information

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• Tripdiolide
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• SCHIZANDRIN B
• 7-HYDROXYCOUMARIN GLUCOSIDE
• DAPHNIN
• 5,7-DIHYDROXYCOUMARIN