CHROMONE-3-CARBOXALDEHYDE Chemical Properties

Melting point:

151-153 °C (lit.)

Boiling point:

245.11°C (rough estimate)

Density 

1.2135 (rough estimate)

refractive index 

1.4500 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

Crystalline Powder

color 

Orange

Sensitive 

Air Sensitive

BRN 

472849

CAS DataBase Reference

17422-74-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Safety Statements 

24/25

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29329900

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

CHROMONE-3-CARBOXALDEHYDE Usage And Synthesis

Chemical Properties

orange crystalline powder

Uses

3-Formylchromone may be used in the following studies:

• Preparation of library of novel (E)-3-(2-arylcarbonyl-3-(arylamino)allyl)-4H-chromen-4-ones, by three-component domino reactions with (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones and anilines under catalyst-free conditions.
• Facile and ecofriendly synthesis of new chromonyl chalcones.
• Synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones.

Synthesis Reference(s)

Tetrahedron Letters, 14, p. 1995, 1973 DOI: 10.1016/S0040-4039(01)96102-7

General Description

Electrospray ionization mass spectrometry (ESI-MS) of protonated 3-formylchromone (3-FC) shows loss of H₂ as a major fragmentation route to yield a ketene cation, which on reaction with water forms a protonated carboxylic acid. The invivo salubrious effects of 3-FC against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis has been investigated. Synthesis and characterization of 3-FC and its derivatives has been reported.

CHROMONE-3-CARBOXALDEHYDE(17422-74-1)Related Product Information

• CHROMONE-3-CARBOXYLIC ACID
• 3-Formyl-6-isopropylchromone
• 6-BROMO-3-FORMYLCHROMONE
• CHROMONE-3-CARBOXALDEHYDE
• 6,8-DICHLORO-3-FORMYLCHROMONE
• 5,7-DIMETHYLCHROMONE-3-CARBOXALDEHYDE
• 2-AMINO-3-FORMYL-6-METHYLCHROMONE
• 2-AMINO-6-CHLORO-3-FORMYLCHROMONE
• CHROMONE
• 6,8-DIMETHYL-3-FORMYLCHROMONE
• 6-FLUORO-3-FORMYLCHROMONE
• 6,7-DIMETHYL-4-OXO-4H-CHROMENE-3-CARBALDEHYDE
• 6-ETHYL-3-FORMYLCHROMONE
• 6-CHLORO-3-FORMYLCHROMONE
• 2-AMINO-6-BROMO-3-FORMYLCHROMONE
• 2-AMINO-3-FORMYL-6,7-DIMETHYLCHROMONE
• 6-CHLORO-3-FORMYL-7-METHYLCHROMONE
• 6,8-DIBROMO-3-FORMYLCHROMONE, 99%