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CHROMONE-3-CARBOXALDEHYDE

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CHROMONE-3-CARBOXALDEHYDE Basic information

Product Name:
CHROMONE-3-CARBOXALDEHYDE
Synonyms:
  • 4H-1-Benzopyran-3-carboxaldehyde, 4-oxo-
  • CHROMONE-3-CARBOXALDEHYDE
  • BUTTPARK 29\06-40
  • AURORA KA-4820
  • 4-oxo-1-benzopyran-3-carboxaldehyde
  • JRH-00101, 4-Oxo-4H-chromene-3-carbaldehyde, 97%
  • AKOS B022468
  • AKOS BBS-00006952
CAS:
17422-74-1
MF:
C10H6O3
MW:
174.15
EINECS:
241-451-5
Product Categories:
  • Chromones
Mol File:
17422-74-1.mol
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CHROMONE-3-CARBOXALDEHYDE Chemical Properties

Melting point:
151-153 °C (lit.)
Boiling point:
245.11°C (rough estimate)
Density 
1.2135 (rough estimate)
refractive index 
1.4500 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder
color 
Orange
Sensitive 
Air Sensitive
BRN 
472849
CAS DataBase Reference
17422-74-1(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Safety Statements 
24/25
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29329900

MSDS

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CHROMONE-3-CARBOXALDEHYDE Usage And Synthesis

Chemical Properties

orange crystalline powder

Uses

3-Formylchromone may be used in the following studies:

  • Preparation of library of novel (E)-3-(2-arylcarbonyl-3-(arylamino)allyl)-4H-chromen-4-ones, by three-component domino reactions with (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones and anilines under catalyst-free conditions.
  • Facile and ecofriendly synthesis of new chromonyl chalcones.
  • Synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones.

Synthesis Reference(s)

Tetrahedron Letters, 14, p. 1995, 1973 DOI: 10.1016/S0040-4039(01)96102-7

General Description

Electrospray ionization mass spectrometry (ESI-MS) of protonated 3-formylchromone (3-FC) shows loss of H2 as a major fragmentation route to yield a ketene cation, which on reaction with water forms a protonated carboxylic acid. The invivo salubrious effects of 3-FC against nitrosodiethylamine (NDEA) mediated early hepatocellular carcinogenesis has been investigated. Synthesis and characterization of 3-FC and its derivatives has been reported.

CHROMONE-3-CARBOXALDEHYDE Preparation Products And Raw materials

Raw materials

CHROMONE-3-CARBOXALDEHYDESupplier

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