Basic information Safety Supplier Related

MONACOLIN J

Basic information Safety Supplier Related

MONACOLIN J Basic information

Product Name:
MONACOLIN J
Synonyms:
  • (4R,6R)-4-Hydroxy-6-(2-((1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)tetrahydro-2H-pyran-2-one
  • 6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
  • (4R,6R)-
  • SiMvastatin Lactone Diol
  • Lovastatin Lactone Diol
  • Lovastatin Diol Lactone
  • Simvastatin EP Impurity H
  • Lovastatin Impurity 8
CAS:
79952-42-4
MF:
C19H28O4
MW:
320.42322
Product Categories:
  • Chiral Reagents
  • Drug Analogues
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
79952-42-4.mol
More
Less

MONACOLIN J Chemical Properties

Melting point:
50-53°C
Boiling point:
535.7±50.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform (Slightly), DMF, DMSO, Methanol (Slightly)
form 
Solid
pka
13.49±0.40(Predicted)
color 
White to Pale Yellow
Stability:
Hygroscopic
More
Less

MONACOLIN J Usage And Synthesis

Chemical Properties

Tan Solid

Uses

Monacolin J is a Simvastatin intermediate; Lovastatin analog has the activities of decreasing blood cholesterol and low-d. lipoprotein, can be used to preparation hypolipidemic medicine.

Definition

ChEBI: A polyketide that is monacolin L bearing an additional hydroxy substituent at position 8.

MONACOLIN JSupplier

Nanjing XiZe Biotechnology CO., Ltd. Gold
Tel
025-66023220 0086-15250997978
Email
1511893459@qq.com
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Jinan Trio PharmaTech Co., Ltd.
Tel
+86 (531) 88811783
Email
sales@trio-pharmatech.com (International market)
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-010-52878169 15801002657
Email
sales@bjcomparison.com