CV-6209
CV-6209 Basic information
- Product Name:
- CV-6209
- Synonyms:
-
- 2-(2-Acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl- pyridinium Chloride
- 2-(N-Acetyl-N-(2-methoxy-3-octadecylcarbamoyloxypropoxycarbonyl)aminomethyl)-1-ethylpyridinium
- Cv 6209 chloride
- Pyridinium, 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-, chloride
- CV-6209 (CV 6209
- Pyridinium, 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-, chloride (1:1)
- CAS:
- 100488-87-7
- MF:
- C34H60ClN3O6
- MW:
- 0
- Product Categories:
-
- Heterocycles
- Inhibitors
- Heterocyclic Compounds
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
- Mol File:
- 100488-87-7.mol
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CV-6209 Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Water: 10 mg/ml
- form
- A crystalline solid
- color
- Off-white to light yellow
- Stability:
- Store at -200C.
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CV-6209 Usage And Synthesis
Description
CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively. It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid , histamine, bradykinin , or isoproterenol . CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.
Chemical Properties
Pale-Yelow Solid
Uses
Competitive PAF receptor antagonist. Inhibits PAF induced human platelet aggregation. Inhibits PAF induced hypotension and lethality.
CV-6209Supplier
J & K SCIENTIFIC LTD.
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