Basic information Safety Supplier Related

CV-6209

Basic information Safety Supplier Related

CV-6209 Basic information

Product Name:
CV-6209
Synonyms:
  • 2-(2-Acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl- pyridinium Chloride
  • 2-(N-Acetyl-N-(2-methoxy-3-octadecylcarbamoyloxypropoxycarbonyl)aminomethyl)-1-ethylpyridinium
  • Cv 6209 chloride
  • Pyridinium, 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-, chloride
  • CV-6209 (CV 6209
  • Pyridinium, 2-(2-acetyl-6-methoxy-3,9-dioxo-4,8-dioxa-2,10-diazaoctacos-1-yl)-1-ethyl-, chloride (1:1)
CAS:
100488-87-7
MF:
C34H60ClN3O6
MW:
0
Product Categories:
  • Heterocycles
  • Inhibitors
  • Heterocyclic Compounds
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:
100488-87-7.mol
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CV-6209 Chemical Properties

storage temp. 
Store at -20°C
solubility 
Water: 10 mg/ml
form 
A crystalline solid
color 
Off-white to light yellow
Stability:
Store at -200C.
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CV-6209 Usage And Synthesis

Description

CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, inhibiting aggregation of rabbit and human platelets induced by PAF with IC50 values of 75 and 170 nM, respectively. It has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is bioavailable, as it prevents PAF-induced hypotension in rats, while not blocking hypotension triggered by arachidonic acid , histamine, bradykinin , or isoproterenol . CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo.

Chemical Properties

Pale-Yelow Solid

Uses

Competitive PAF receptor antagonist. Inhibits PAF induced human platelet aggregation. Inhibits PAF induced hypotension and lethality.

CV-6209Supplier

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