Ristocetin
Ristocetin Basic information
- Product Name:
- Ristocetin
- Synonyms:
-
- Ristomycin A
- Ristocetin, RistoMycin III, Spontin, Riston
- CAS:
- 11021-66-2
- MF:
- C95H110N8O44
- MW:
- 2067.92
- Mol File:
- 11021-66-2.mol
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Ristocetin Chemical Properties
- alpha
- D -120 to -133° (water)
- Density
- 1.76±0.1 g/cm3(Predicted)
- pka
- 8.55±0.70(Predicted)
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Safety Information
- RIDADR
- 3249
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- mouse,LD50,intravenous,1350mg/kg (1350mg/kg),SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE,"Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 568, 1967.
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Ristocetin Usage And Synthesis
Uses
Ristocetin A sulfate is a potent antibacterial glycopeptide antibiotic that was withdrawn from clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease, leading to the use of ristocetin A as an important diagnostic aid.
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Ristocetin(11021-66-2)Related Product Information
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- Methyl 3,5-dihydroxyphenylacetate
- (S)-3,5-DIHYDROXYPHENYLGLYCINE
- 1,1-Dimethoxy-2-(2-methoxyethoxy)ethane
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- CHEMBRDG-BB 5537265
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- Ristocetin
- (RS)-3,5-DHPG
- 2-[4-(2,3-DIHYDROXYPROPOXY)PHENYL]ACETAMIDE
- (S)-AMINO-O-TOLYL-ACETIC ACID
- AC-PHG-OME