Basic information Safety Supplier Related

Tepoxalin

Basic information Safety Supplier Related

Tepoxalin Basic information

Product Name:
Tepoxalin
Synonyms:
  • 3-[1-(4-Methoxyphenyl)-5-(4-chlorophenyl)-1H-pyrazol-3-yl]-N-hydroxy-N-methylpropanamide
  • RWJ-20485
  • 5-(4-Chlorophenyl)-N-hydroxy-1-(4-Methoxyphenyl)-N-Methyl-1H-pyrazole-3-propanaMide
  • ORF 20485
  • 3-(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-1H-pyrazol-3-yl)-N-hydroxy-N-methylpropanamide
  • Tepoxalin
  • 1H-Pyrazole-3-propanamide, 5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-
  • epoxalin
CAS:
103475-41-8
MF:
C20H20ClN3O3
MW:
385.849
Product Categories:
  • Amines
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
103475-41-8.mol
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Tepoxalin Chemical Properties

Melting point:
124-126°
storage temp. 
Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility 
DMSO (Sparingly), Methanol (Slightly)
form 
Solid
color 
White to Pale Brown
Stability:
Hygroscopic
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Tepoxalin Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

Non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties approved for veterinary use. It has inhibitory effect on cyclooxygenase and 5-lipxygenase activity as well as inhibiting the production of cytokines in peripheral cells outside the CNS.

Uses

Tepoxalin is non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties approved for veterinary use. It has inhibitory effect on cyclooxygenase and 5-lipxygenase activity a s well as inhibiting the production of cytokines in peripheral cells outside the CNS.

Definition

ChEBI: A hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the contr l of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs.

Veterinary Drugs and Treatments

Tepoxalin is indicated for the treatment of pain and inflammation associated with osteoarthritis in dogs. Because of the drug’s inhibitory effects on leukotrienes, there is interest in seeing if it would be beneficial in the adjunctive treatment of allergic conditions in dogs.

TepoxalinSupplier

Shanghai Boyle Chemical Co., Ltd.
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Email
sales@boylechem.com
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
ZHIWE CHEMTECH CO LTD
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021-20221225 13917446399
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sales@zhiwe.net
Chemsky(shanghai)International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
Hangzhou Yuhao Chemical Technology Co., Ltd
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0571-82693216
Email
info@yuhaochemical.com