4-CYANOPHENYLACETIC ACID Chemical Properties

Melting point:

150-154 °C(lit.)

Boiling point:

355.2±25.0 °C(Predicted)

Density 

1.26±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in CHCl3, THF, dioxane.

pka

3.93±0.10(Predicted)

form 

Powder

color 

White to pale brown

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/38

Safety Statements 

26

RIDADR 

UN3439

WGK Germany 

3

HazardClass 

6.1

PackingGroup 

III

HS Code 

29269090

MSDS

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4-CYANOPHENYLACETIC ACID Usage And Synthesis

Chemical Properties

Off-white crystals

Uses

4-Cyanophenylacetic acid can be used as a nitrile precursor to synthesize 1,2,4,5-tetrazines by reacting with aliphatic nitriles and hydrazine in the presence of Lewis acid metal catalysts.
It can also be used as a reactant to prepare:

• 4-pyrrolo[1,2-a]quinoxalin-4-ylbenzonitrile by copper-catalyzed reaction with 1-(2-aminoaryl)pyrrole in the presence of 2,2′-bipyridyl as the ligand.
• 4-(1,2-Diphenyl-1H-imidazol-4-yl)benzonitrile by one-pot three-component reaction with N-phenylbenzamidine and nitromethane via activation of C-H and N-H bonds.
• 4-Cyano-N,N-di-2-propen-1-ylbenzeneacetamide by reacting with diallylamine.

4-CYANOPHENYLACETIC ACID(5462-71-5)Related Product Information

• 3-Bromophenylacetic acid
• 4-Chlorophenylacetic acid
• 4-Bromophenylacetic acid
• 2,5-Dimethylphenylacetic acid
• 3,4-Difluorophenylacetic acid
• 2-Chloro-6-fluorophenylacetic acid
• 3,5-Difluorophenylacetic acid
• 2-CHLORO-5-FLUOROPHENYLACETIC ACID
• 3-Chlorophenylacetic acid
• 3,4-Dichlorophenylacetic acid
• 2-(3,5-dichlorophenyl)acetic acid
• 2,6-Dichlorophenylacetic acid
• (2-CYANOPHENYL)ACETIC ACID
• 3-Cyanophenylacetic acid ethyl ester
• (2-CYANO-PHENYL)-ACETIC ACID ETHYL ESTER
• 4-Cyanophenylacetic acid ethyl ester
• 3-CYANOPHENYLACETIC ACID
• METHYL (4-CYANOPHENYL)ACETATE