BOLTON-HUNTER REAGENT Chemical Properties

Melting point:

132-133 °C(lit.)

Boiling point:

406.49°C (rough estimate)

Density 

1.2705 (rough estimate)

refractive index 

1.5480 (estimate)

storage temp. 

-20°C

solubility 

Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)

form 

Solid

pka

9.93±0.15(Predicted)

color 

White to Light Orange

Water Solubility 

Soluble in water.

BRN 

1545011

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

10-21

HS Code 

2928009090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

BOLTON-HUNTER REAGENT Usage And Synthesis

Chemical Properties

white to off-white powder

Uses

Bolton-Hunter Reagent is used for iodination of proteins that do not contain tyrosine residues, Bolton-Hunter reagent precursor (3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester) is a hydroxysuccinimide ester used as an intermediate for high radioactive radioiodination of proteins.

Uses

3-(4-Hydroxyphenyl)propionic acid?N-hydroxysuccinimide ester can be used to prepare ¹²⁵I-labeled reagents, which are used in binding assay studies of proteins and peptides.

BOLTON-HUNTER REAGENT(34071-95-9)Related Product Information

• Succinimidyl Myristate
• BOLTON-HUNTER REAGENT
• Succinimide
• N-Hydroxysuccinimide
• 3-(4-Hydroxyphenyl)propionic acid
• FMOC-O-T-BUTYL-L-TYROSINE N-HYDROXYSUCCINIMIDE ESTER
• BOC-D-TYR(BZL)-OSU
• BOC-3,5-DIIODO-TYR-OSU
• N-SUCCINIMIDYL 7-HYDROXY-4-COUMARINYL-AC
• FMOC-O-BUTYL-L-TYROSINE N-HYDROXYSUCCINIMIDE ESTER
• BOLTON-HUNTER REAGENT, [125I],BOLTON-HUNTER REAGENT, [125I] DIIODINATED,BOLTON-HUNTER REAGENT, [125I] (MONOIODINATED)
• BOC-TYR(BZL)-OSU
• Z-TYR(BZL)-OSU
• BOC-TYR-OSU
• WATER-SOLUBLE BOLTON-HUNTER REAGENT
• 7-Methoxycoumarin-4-acetic Acid N-Succinimidyl Ester
• Acridinium C2 NHS Ester
• Z-TYR(TBU)-OSU