chaparrinone Chemical Properties

Melting point:

238-242 °C

Boiling point:

626.1±55.0 °C(Predicted)

Density 

1.45±0.1 g/cm3(Predicted)

pka

12.03±0.70(Predicted)

chaparrinone Usage And Synthesis

Uses

Chaparrinone is a quassinoid that can be isolated from the root of Eurycoma harmandiana. Chaparrinone has antimalarial and cytotoxic activities against Plasmodium falciparum and P-388 cells (IC50: 0.037 and 0.34 μg/mL respectively)[1][2].

Definition

ChEBI: Chaparrinone is a triterpenoid.

References

[1] Kanchanapoom T, et al. Quassinoids from Eurycoma harmandiana. Phytochemistry. 2001 Aug;57(8):1205-8. DOI:10.1016/s0031-9422(01)00235-7
[2] Fran?ois G, et al. Antimalarial and cytotoxic potential of four quassinoids from Hannoa chlorantha and Hannoa klaineana, and their structure-activity relationships. Int J Parasitol. 1998 Apr;28(4):635-40. DOI:10.1016/s0020-7519(98)00008-3

chaparrinone(22611-34-3)Related Product Information

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