mastoparan B
mastoparan B Basic information
- Product Name:
- mastoparan B
- Synonyms:
-
- mastoparan B
- L-Leucinamide, L-leucyl-L-lysyl-L-leucyl-L-lysyl-L-seryl-L-isoleucyl-L-valyl-L-seryl-L-tryptophyl-L-alanyl-L-lysyl-L-lysyl-L-valyl-
- mast cell degranulatingpeptide (vespa basalis)
- LKLKSIVSWAKKVL-NH2
- CAS:
- 137354-65-5
- MF:
- C78H138N20O16
- MW:
- 1612.05
- Mol File:
- 137354-65-5.mol
mastoparan B Chemical Properties
- Sequence
- Leu-Lys-Leu-Lys-Ser-Ile-Val-Ser-Trp-Ala-Lys-Lys-Val-Leu-NH2
mastoparan B Usage And Synthesis
Chemical Properties
Isolated from the venom of the Taiwan hornet Vespa basalis.
Uses
Mastoparan B is an antimicrobial peptide derived from hornet Vespa. Mastoparan B can cause the shape of red blood cells to change from normal disk-like to serrated[1].
Definition
ChEBI: A member of the class of mastopyrans that is a 14-amino acid polypeptide comprising leucyl, lysyl, leucyl, lysyl, seryl, isoleucyl, valyl, seryl, tryptophyl, alanyl, lysyl, lysyl, valyl, and leucinamide residues coupled in sequence. It is the major active omponent of the venom of the hornet Vespa basalis and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocy es.
Hazard
A poison.
References
[1] Park NG, et al. Interaction of mastoparan-B from venom of a hornet in Taiwan with phospholipid bilayers and its antimicrobial activity. Biopolymers. 1995 Dec;36(6):793-801. DOI:10.1002/bip.360360611
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