5,5'-DIFLUORO BAPTA, AM
5,5'-DIFLUORO BAPTA, AM Basic information
- Product Name:
- 5,5'-DIFLUORO BAPTA, AM
- Synonyms:
-
- 1,2-BIS(2-AMINO-5-FLUOROPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID TETRAKIS(ACETOXYMETHYL) ESTER
- 5,5'-DIFLUORO BAPTA, AM
- acetyloxymethyl 2-[N-[2-(acetyloxymethoxy)-2-oxoethyl]-2-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-4-fluorophenoxy]ethoxy]-5-fluoroanilino]acetate
- Glycine, N,N'-[1,2-ethanediylbis[oxy(5-fluoro-2,1-phenylene)]]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-, bis[(acetyloxy)methyl] ester (9CI)
- CAS:
- 156027-00-8
- MF:
- C34H38F2N2O18
- MW:
- 800.66
- Mol File:
- 156027-00-8.mol
5,5'-DIFLUORO BAPTA, AM Chemical Properties
- Boiling point:
- 799.9±60.0 °C(Predicted)
- Density
- 1.393±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- 0.60±0.50(Predicted)
MSDS
- Language:English Provider:SigmaAldrich
5,5'-DIFLUORO BAPTA, AM Usage And Synthesis
Uses
5,5'-Difluoro BAPTA is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA is the most widely used probe for studying cytosolic free Ca2+ by 19F NMR. 5,5'-Difluoro BAPTA has high selectivity for Ca2+. 5,5'-Difluoro BAPTA can inhibit the growth of pollen tube[1][2].
References
[1] Bar-Shir A, et al. Metal ion sensing using ion chemical exchange saturation transfer 19F magnetic resonance imaging. J Am Chem Soc. 2013 Aug 21;135(33):12164-7. DOI:10.1021/ja403542g
[2] Pierson ES, et al. Pollen tube growth is coupled to the extracellular calcium ion flux and the intracellular calcium gradient: effect of BAPTA-type buffers and hypertonic media. Plant Cell. 1994 Dec;6(12):1815-28. DOI:10.1105/tpc.6.12.1815
[3] Kostellow AB, et al. Iron-catalyzed lipid peroxidation in aortic cells in vitro: protective effect of extracellular magnesium. Atherosclerosis. 2004 Jul;175(1):15-22. DOI:10.1016/j.atherosclerosis.2004.01.040