5,6-DIHYDROXYINDOLE Chemical Properties

Melting point:

140 °C (decomp)

Boiling point:

411.2±25.0 °C(Predicted)

Density 

1.510±0.06 g/cm3(Predicted)

RTECS 

NL7858000

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml

form 

Solid

pka

9.81±0.40(Predicted)

color 

Off-white to light brown

InChI

InChI=1S/C8H7NO2/c10-7-3-5-1-2-9-6(5)4-8(7)11/h1-4,9-11H

InChIKey

SGNZYJXNUURYCH-UHFFFAOYSA-N

SMILES

N1C2=C(C=C(O)C(O)=C2)C=C1

LogP

0.370 (est)

Safety Information

Hazard Codes 

Xn,N

Risk Statements 

22-41-51/53

Safety Statements 

22-26-36/37/39-61

HS Code 

2933998090

5,6-DIHYDROXYINDOLE Usage And Synthesis

Description

5,6-Dihydroxyindole is a melanin precursor. It is one of the toxic compounds in the melanin biosynthetic pathway. 5,6-Dihydroxyindole is an indole derivative that contains two hydroxyl groups attached to the 5th and 6th positions of the indole ring. It is an intermediate in the biosynthesis of melanin, a pigment responsible for the coloration of hair, skin, and eyes in humans and other organisms.

Uses

5,6-Dihydroxyindole is an intermediate in melanogenesis, the production of melanin which is found in our skin, eyes, hair, and inner ear.

Definition

ChEBI: 5,6-dihydroxyindole is a dihydroxyindole. It has a role as a mouse metabolite.

Synthesis Reference(s)

Synthetic Communications, 15, p. 321, 1985 DOI: 10.1080/00397918508063806

5,6-DIHYDROXYINDOLE(3131-52-0)Related Product Information

• N,N-dimethyldopamine
• Methanone, [4-(2-aminoethyl)phenyl]phenyl-
• ETHYL 5,6-DIMETHOXYINDOLE-2-CARBOXYLATE
• 5,6-METHYLENEDIOXY-2-PHENYLINDOLE
• 5,6-DIHYDROXYINDOLE
• Solypertine
• oxypertine
• 5,6-DIMETHOXY-2-PHENYLINDOLE
• Alpertine
• 5,6-Dimethoxyindole
• 6-HYDROXYMELATONIN
• 5,6-DIMETHOXYINDOLE-2-CARBOXYLIC ACID
• 5-Benzyloxy-6-methoxyindole
• 5,6-DIBENZYLOXYINDOLE
• METHYL-6,7-DIMETHOXY-4-ETHYL-BETA-CARBOLINE-3-CARBOXYLATE
• 5,6-DIACETOXYINDOLE
• 5-hydroxy-6-methoxyindole
• 6-BENZYLOXY-5-METHOXYINDOLE-2-CARBOXYLIC ACID