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(1S,2S)-trans-N-Boc-2-aminocyclopentanol

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(1S,2S)-trans-N-Boc-2-aminocyclopentanol Basic information

Product Name:
(1S,2S)-trans-N-Boc-2-aminocyclopentanol
Synonyms:
  • (1S,2S)-trans-N-Boc-2-aminocyclopentanol
  • tert-butyl (1S,2S)-2-hydroxycyclopentylcarbamate
  • ((1S,2S)-2-Hydroxycyclopentyl)carbamic acid tert-butyl ester
  • tert-Butyl N-((2S,1S)-2-hydroxycyclopentyl)carbamate
  • (1S,2S)-trans-N-Boc-2-aminocyclopentanol 99%
  • (1S,2S)-2-(Boc-amino)cyclopentanol
  • Carbamic acid,N-[(1S,2S)-2-hydroxycyclopentyl]-, 1,1-dimethylethyl ester
  • tert-butyl (1S,2S)-2-hydroxycyclopentyl
CAS:
145106-43-0
MF:
C10H19NO3
MW:
201.26
Product Categories:
  • apis
  • Amino Alcohols
  • Chiral Building Blocks
  • Organic Building Blocks
Mol File:
145106-43-0.mol
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(1S,2S)-trans-N-Boc-2-aminocyclopentanol Chemical Properties

Melting point:
87.0℃
Boiling point:
320.8±31.0 °C(Predicted)
Density 
1.08±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Sealed in dry,Room Temperature
pka
12.09±0.40(Predicted)
Appearance
White to off-white Solid
optical activity
-23.2° (C=0.93 g/100ml CH2CL2)
BRN 
5810036
InChI
InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-7-5-4-6-8(7)12/h7-8,12H,4-6H2,1-3H3,(H,11,13)/t7-,8-/m0/s1
InChIKey
CGZQRJSADXRRKN-YUMQZZPRSA-N
SMILES
C(OC(C)(C)C)(=O)N[C@H]1CCC[C@@H]1O
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
22-50
Safety Statements 
61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
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(1S,2S)-trans-N-Boc-2-aminocyclopentanol Usage And Synthesis

Uses

Reactant for:

  • Asymmetric synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors via stereoselective thioesterification, thioetherification, hydrolysis, heterocyclization and amination

(1S,2S)-trans-N-Boc-2-aminocyclopentanolSupplier

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