3β-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranuronosyl)oxy]oleana-12-ene-28-oic acid Chemical Properties

Boiling point:

910.4±65.0 °C(Predicted)

Density 

1.37±0.1 g/cm3(Predicted)

storage temp. 

4°C, protect from light

solubility 

DMSO: soluble; Ethanol: soluble

form 

A solid

pka

2.76±0.70(Predicted)

color 

White to off-white

InChIKey

WJQOMUVKRDJBGZ-RLRHDSBLNA-N

3β-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranuronosyl)oxy]oleana-12-ene-28-oic acid Usage And Synthesis

Uses

Zingibroside R1 is dammaranae-type triterpenoid saponin, isolated from rhizomes, taproots, and lateral roots of Panax japonicas C. A. Meyer, shows excellent anti-tumor effects as well as anti-angiogenic activity[1]. Zingibroside R1 possesses some anti-HIV-1 activity. Zingibroside R1 has inhibitory effects on the 2-deoxy-D-glucose (2-DG) uptake by EAT cells (IC50=91.3 μM)[2].

IC 50

HIV-1

References

[1] Yoshizaki K, et al. Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). Chem Pharm Bull (Tokyo). 2013;61(3):344-50. Epub 2012 Dec 28 DOI:10.1248/cpb.c12-00764
[2] Hasegawa H, et al. Inhibitory effect of some triterpenoid saponins on glucose transport in tumor cells and its application to in vitro cytotoxic and antiviral activities. Planta Med. 1994 Jun;60 (3):240-3. DOI:10.1055/s-2006-959467

3β-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranuronosyl)oxy]oleana-12-ene-28-oic acid(80930-74-1)Related Product Information

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