Muramyl Dipeptide
Muramyl Dipeptide Basic information
- Product Name:
- Muramyl Dipeptide
- Synonyms:
-
- acetylmuramyl-alanyl-isoglutamine
- n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamin
- n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamine
- Ac-muramyl-Ala-D-Glu-NH
- N-AC-MURAMYL-ALA-D-GLU-NH2
- N-AC-MURAMYL-ALA-D-GLU-NH2 2H2O
- N-ACETYL-MURAMYL-L-ALA-D-ISOGLN
- N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE
- CAS:
- 53678-77-6
- MF:
- C19H32N4O11
- MW:
- 492.48
- EINECS:
- 258-696-9
- Mol File:
- 53678-77-6.mol
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Muramyl Dipeptide Chemical Properties
- Boiling point:
- 1071.8±65.0 °C(Predicted)
- alpha
- D25 +44° (acetic acid)
- Density
- 1.390±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- H2O: 10 mg/mL, clear, colorless
- pka
- 4.44±0.10(Predicted)
- form
- buffered aqueous solution
- color
- White to off-white
- Merck
- 13,6329
- BRN
- 4220745
- CAS DataBase Reference
- 53678-77-6(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
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Muramyl Dipeptide Usage And Synthesis
Uses
N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate has been used in staphylococcal cell wall preparation to induce the release of TNF from human monocytes.
Uses
Immunological adjuvant.
Biochem/physiol Actions
Muramyl peptides are monomeric components that make up the bacterial cell wall peptidoglycan. It is generally produced by mammalian macrophages, as an immune response in the breakdown of bacterial cell wall. MDP promotes the production of interleukin-1 and tumor necrosis factor (TNF), which increase slow-wave sleep.
Muramyl DipeptideSupplier
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Muramyl Dipeptide(53678-77-6)Related Product Information
- N-ACETYLMURAMYL-D-ALANYL-D-ISOGLUTAMINE)
- N-ACETYLMURAMYL-L-ALANYL-L-ISOGLUTAMINE
- pro-val-gly-leu-lle-gly
- syn-coll
- FREUND'S COMPLETE ADJUVANT
- 1-ALPHA-O-BENZYL-N-ACETYLMURAMYL-ALA-D-ISOGLN-LYS(TRANS(M-NITROCINNAMOYL)-NH2)-NH2
- Romurtide
- Temurtide
- N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAROYL
- Muramyl Dipeptide
- N-ACETYL-D-GLUCOSAMINYL-Β-(1→4)-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
- N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE-6-O-STEAR
- GMDP
- AC-(6-O-STEAROYL)-MURAMYL-ALA-D-GLU-NH2