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Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester

Basic information Safety Supplier Related

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Basic information

Product Name:
Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester
Synonyms:
  • 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]
  • ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate
  • Apixaban Impurity B
  • (Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (Apixaban)
  • Apixaban-2
  • 1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide
  • Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester
  • Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate
CAS:
27143-07-3
MF:
C11H13ClN2O3
MW:
256.69
EINECS:
608-053-7
Product Categories:
  • 27143-07-3
Mol File:
27143-07-3.mol
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Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Chemical Properties

Melting point:
94℃
Boiling point:
349.0±44.0 °C(Predicted)
Density 
1.23
storage temp. 
2-8°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
Solid
pka
11.63±0.10(Predicted)
color 
Yellow to Dark Yellow
InChI
InChI=1S/C11H13ClN2O3/c1-3-17-11(15)10(12)14-13-8-4-6-9(16-2)7-5-8/h4-7,13H,3H2,1-2H3
InChIKey
ATNPZEGMKLGIFA-UHFFFAOYSA-N
SMILES
C(OCC)(=O)C(Cl)=NNC1=CC=C(OC)C=C1
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Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester Usage And Synthesis

Physical properties

Light yellow to dark yellow solid

Uses

Acetic acid, 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene], ethyl ester is an ester derivative and can be used as an intermediate in the synthesis of apixaban.

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