Basic information Safety Supplier Related

α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers)

Basic information Safety Supplier Related

α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers) Basic information

Product Name:
α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers)
Synonyms:
  • α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers)
  • 8-hydroxy-3-(4-hydroxy-5-hydroxymethyl-tetra-hydrofuran-2-yl)-6-methyl-5,6,7,8-tetrahydro-3H-1,3,4,5,8a-pentaaza-cyclopenta[b]naphthalen-9-one
  • 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-4,6,7,8-tetrahydro-8-hydroxy-6-MethylpyriMido[1,2-a]purin-10(3H)-one
  • α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine
  • Pyrimido[1,2-a]purin-10(3H)-one, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-4,6,7,8-tetrahydro-8-hydroxy-6-methyl-
  • α-Methyl-γ-hydroxy-1,N2-propano-2’-deoxyguanosine (Mixture of Diastereomers)
  • 3-(2-Deoxy-β-D-erythro-pentofuranosyl)-4,6,7,8-tetrahydro-8-hydroxy-6-methylpyrimido[1,2-a]purin-10(3H)-one
CAS:
132014-87-0
MF:
C14H19N5O5
MW:
337.34
Product Categories:
  • Carbohydrates & Derivatives
  • Heterocycles
  • Mutagenesis Research Chemicals
Mol File:
132014-87-0.mol
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α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers) Chemical Properties

Melting point:
135-137°C
Boiling point:
724.7±70.0 °C(Predicted)
Density 
1.93±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
pka
11.80±0.40(Predicted)
color 
White to Light Yellow
Stability:
Hygroscopic
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α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers) Usage And Synthesis

Chemical Properties

White Solid

Uses

A genotoxic cyclic adduct of 2''-deoxyguanosine with crotonaldehyde. Histones accelerate the cyclic 1,N2-propanoguanine adduct-formation of DNA by the primary metabolite of alcohol and carcinogenic crotonaldehyde.

Uses

A genotoxi crotonaldehyde.

α-Methyl-γ-hydroxy-1,N2-propano-2'-deoxyguanosine (Mixture of DiastereoMers)Supplier

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