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2-Methyl-D-phenylalanine

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2-Methyl-D-phenylalanine Basic information

Product Name:
2-Methyl-D-phenylalanine
Synonyms:
  • N-ME-D-PHENYLALANINE
  • N-ME-D-PHE-OH
  • N-METHYL-D-PHENYLALANINE
  • (R)-2-METHYLPHENYLALANINE
  • (R)-2-AMINO-2-METHYL-3-PHENYLPROPANOIC ACID
  • (R)-2-AMINO-2-METHYL-3-PHENYLPROPIONIC ACID
  • N-ALPHA-METHYL-D-PHENYLALANINE
  • ALPHA-BENZYL-D-ALA
CAS:
17350-84-4
MF:
C10H13NO2
MW:
179.22
Product Categories:
  • α-Methyl Amino Acids
  • unnatural amino acids
  • Unusual amino acids
  • pharmacetical
  • Chiral Reagent
Mol File:
17350-84-4.mol
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2-Methyl-D-phenylalanine Chemical Properties

Melting point:
277-279 °C(Solv: acetone (67-64-1))
Boiling point:
312.8±30.0 °C(Predicted)
Density 
1.166±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
Powder
pka
2.25±0.10(Predicted)
color 
White to pale yellow
BRN 
5254151
CAS DataBase Reference
17350-84-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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2-Methyl-D-phenylalanine Usage And Synthesis

Chemical Properties

White powder

Uses

α-Methyl-D-phenylalanine is used to prepare hippuryl-α-methylphenylalanine and hippuryl-α-methylphenyllactic acid as substrates for carboxypeptidase A. It is also used in the synthesis of high affinity tachykinin NK2 receptor antagonists.

Uses

2-Methyl-D-phenylalanine is a derivative of D-Phenylalanine (P319410); the stereoisomer of L-Phenylalanine (P319415) used in the synthesis of Schaeffer’s acid analogs as important structures in tuberculostatic design. These analogs exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.

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