N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1S,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide Chemical Properties

Boiling point:

726.6±70.0 °C(Predicted)

Density 

1.55

storage temp. 

Store at -20°C

solubility 

≥ 47.6 mg/mL in DMSO, ≥ 99.4 mg/mL in EtOH with ultrasonic

pka

4.97±0.20(Predicted)

form 

Powder

color 

White to off-white

N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1S,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide Usage And Synthesis

Uses

N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1S,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide is a potent and selective CXCR2 ligand. It is also a SIRT1 activator.

IC 50

CXCR2

N-[2-[[(2,3-Difluorophenyl)methyl]thio]-6-[[(1S,2R)-2,3-dihydroxy-1-methylpropyl]amino]-4-pyrimidinyl]-1-azetidinesulfonamide(1204707-73-2)Related Product Information

• 4-Aminodiphenylamine
• N-Methylbenzamide