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(R)-XL518

Basic information Safety Supplier Related

(R)-XL518 Basic information

Product Name:
(R)-XL518
Synonyms:
  • CobiMetinib (R-enantioMer)
  • GDC-0973 R-ENANTIOMER;XL-518 R-ENANTIOMER
  • Cobimetinib R-enantiomer (GDC-0973 R-enantiomer
  • (R)-Cobimetinib
  • (R)-XL518
  • [3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]phenyl][3-hydroxy-3-[(2R)-2-piperidinyl]-1-azetidinyl]Methanone
  • GDC-0973 (R-enantioMer)
  • XL-518 (R-enantioMer)
CAS:
934660-94-3
MF:
C21H21F3IN3O2
MW:
531.31
Product Categories:
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Protein Kinase Inhibitors and Activators
Mol File:
934660-94-3.mol
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(R)-XL518 Chemical Properties

Boiling point:
565.9±50.0 °C(Predicted)
Density 
1.706±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
13.13±0.20(Predicted)
form 
Powder
color 
White to off-white
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Safety Information

HS Code 
2934999090
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(R)-XL518 Usage And Synthesis

Uses

The (R)-enantiomer of the MEK1 inhibitor XL518 (X746250).

(R)-XL518Supplier

Chemsky (shanghai) International Co.,Ltd
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Haoyuan Chemexpress Co., Ltd.
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