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VUF11207

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VUF11207 Basic information

Product Name:
VUF11207
Synonyms:
  • VUF11207
  • (E)-N-(3-(2-fluorophenyl)-2-Methylallyl)-3,4,5-triMethoxy-N-(2-(1-Methylpyrrolidin-2-yl)ethyl)benzaMide
  • (E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)benzamide trifluoroacetate salt
  • N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-benzamide trifluoroacetate salt
  • VUF11207 trifluoroacetate salt
  • VUF11207 Triflate
  • (E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)
  • VUF11207;VUF-11207;VUF 11207
CAS:
1378524-41-4
MF:
C27H35FN2O4
MW:
470.58
Mol File:
1378524-41-4.mol
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VUF11207 Chemical Properties

Boiling point:
615.9±55.0 °C(Predicted)
Density 
1.134±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: soluble5mg/mL, clear (warmed)
pka
10.26±0.40(Predicted)
form 
oil
color 
white to beige
Water Solubility 
H2O: 5mg/mL, clear (warmed)
InChIKey
GZXNWMFPSYCITC-QTCZRQAZSA-N
SMILES
O=C(N(CCC1N(C)CCC1)C/C(C)=C/C2=C(F)C=CC=C2)C3=CC(OC)=C(OC)C(OC)=C3.OC(C(F)(F)F)=O
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Safety Information

WGK Germany 
3
Storage Class
11 - Combustible Solids
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VUF11207 Usage And Synthesis

Biological Activity

VUF11207 is a highly potent CXCR7 agonist. VUF11207 induces recruitment of β-arrestin2 to the CXCR7 followed by internalization of the receptor.', 'VUF11207 is considered as a selective inhibitor of CXCR4 (C-X-C motif chemokine receptor 4).

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