STF-118804
STF-118804 Basic information
- Product Name:
- STF-118804
- Synonyms:
-
- STF-118804
- Benzamide, 4-[5-methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)-
- 4-[5-Methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)benzamide
- 4-(5-methyl-4-((phenylsulfonyl)methyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide
- CS-1510
- STF-118804, AGN-PC-0329XY, AKOS001906141, MCULE-5035356713
- AGN-PC-0329XY
- AGN-PC-0329XY; AKOS001906141; MCULE-5035356713; STF-118804
- CAS:
- 894187-61-2
- MF:
- C25H23N3O4S
- MW:
- 461.53
- Product Categories:
-
- Inhibitors
- Mol File:
- 894187-61-2.mol
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STF-118804 Chemical Properties
- Melting point:
- 187-190°C
- Density
- 1.281±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.00±0.46(Predicted)
- color
- White to Off-White
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STF-118804 Usage And Synthesis
Uses
STF-118804 is a highly specific NAMPT inhibitor, improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and targets leukemia stem cells.
Biological Activity
STF-118804 displays pancreatic ductal adenocarcinoma (PDAC) growth reducing potential in combination with chemotherapeutic drugs.', 'STF-118804 is a highly specific and potent NAMPT (nicotinamide phosphoribosyl transferase) inhibitor th at reduces the viability of most B-ALL cell lines. STF 118804 induces leukemia cell apoptosis including leukemia initiating (stem) cells. STF 118804 improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.
storage
Store at -20°C
STF-118804Supplier
Shanghai Boyle Chemical Co., Ltd.
- Tel
- sales@boylechem.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
Haoyuan Chemexpress Co., Ltd.
- Tel
- 021-58950125
- info@chemexpress.com
AdooQ Bioscience CHINA
- Tel
- 025-58849295 18951903616;
- info@adooq.cn
Hubei Jusheng Technology Co.,Ltd
- Tel
- 027-59599241 18871490274
- 1400878000@qq.com