2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride Chemical Properties

Boiling point:

320.8±32.0 °C(Predicted)

Density 

1.317±0.06 g/cm3(Predicted)

pka

12.37±0.70(Predicted)

2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride Usage And Synthesis

Uses

2-Amino-6-fluoro-N-phenylbenzamide is used as reactant/reagent in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step. 2-Amino-6-fluoro-N-phenyl-benzamide is obtained from 2-fluoro-6-nitro-benzoic acid.

2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride(1417456-04-2)Related Product Information

• Idelalisib Impurity 8
• (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
• CAL-101