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5-CHLORO-2-NITROANISOLE

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5-CHLORO-2-NITROANISOLE Basic information

Product Name:
5-CHLORO-2-NITROANISOLE
Synonyms:
  • 4-chloro-2-methoxy-1-nitro-benzen
  • 5-CHLORO-2-NITROANISOLE
  • 4-CHLORO-2-METHOXYNITROBENZENE
  • 4-Chloro-2-methoxynitrobenzene 98%
  • 4-chloro-2-methoxy-1-nitro-benzene
  • 4-Chloro-3-methoxy-1-nitrobenzene
  • 5-CHLORO-2-NITROANISOLE 97%
  • 5-Chloro-2-nitroanisole,97%
CAS:
6627-53-8
MF:
C7H6ClNO3
MW:
187.58
EINECS:
229-594-1
Product Categories:
  • Building Blocks
  • Chemical Synthesis
  • Anisole
  • Nitro Compounds
  • Nitrogen Compounds
  • Organic Building Blocks
  • blocks
  • NitroCompounds
  • Miscellaneous
  • Nitro Compounds
  • Nitrogen Compounds
  • Organic Building Blocks
Mol File:
6627-53-8.mol
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5-CHLORO-2-NITROANISOLE Chemical Properties

Melting point:
70-72 °C(lit.)
Boiling point:
289.1±20.0 °C(Predicted)
Density 
1.4219 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform, Ethyl Acetate
form 
Solid
color 
Yellow
CAS DataBase Reference
6627-53-8(CAS DataBase Reference)
EPA Substance Registry System
5-Chloro-2-nitroanisole (6627-53-8)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36
WGK Germany 
3
HS Code 
2909309090

MSDS

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5-CHLORO-2-NITROANISOLE Usage And Synthesis

Chemical Properties

SLIGHTLY YELLOW TO GREEN CRYSTALLINE POWDER

Uses

5-Chloro-2-nitroanisole is involved in the synthesis of orally bioavailable anaplastic lymphoma kinases (ALK) inhibitors as anticancer drugs (1). In addition, it is used in the synthesis of kinesin spindle protein (KSP) inhibitors which are responsible for the spindle pole separation which occurs during mitosis in cancer cells (2).

5-CHLORO-2-NITROANISOLE Preparation Products And Raw materials

Raw materials

5-CHLORO-2-NITROANISOLESupplier

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